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KMID : 0032219890010020073
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Annals of Dermatology
1989 Volume.1 No. 2 p.73 ~ p.73
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Epidermolysis Bullosa Acquisita
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이창우:Lee Chang-Woo
양홍윤:Yang Hong-Yoon/박문향:Park Moon-Hyang
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Abstract
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A 40-year-old woman had a pruritic, vesiculobullous eruption of her face for 6 weeks with no evidence of systemic disease. A biopsy showed subepidermal blisters and dermal infiltrates of neutrophilic inflammatory cells. Direct immunofluorescence demonstrated thick linear deposits of IgG and C3 along the basement membrane zone. The cleavage plane was identified to be just beneath the lamina densa. Using Western immunoblots, the patient’s IgG autoantibodies were found to recognize type VII proeollagen. Moderate starting doses of systemic prednisolone gave a good response for this patient with an early inflammatory form of epidermolysis bullosa acquisita.
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KEYWORD
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Early inflammatory form, Epidermolysis bullosa acquisita
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